13_3_5

Volume 13, Number 3, pages 66 - 68

New paradigms in immunosuppression

By Robert Huizinga, RN, CNeph(C), and Therese Voyer, BScN, CNeph(C)

Abstract

With the decrease in donor quality and the increase in recipient co-morbidities, transplantation immunosuppression is changing. New paradigms in transplantation include co-stimulation, lymphocyte retrafficking, and inhibiting antibody production. With these new paradigms come new immunosuppressive agents. While these new agents show great promise, their use in day-to-day clinical transplantation remains to be seen.

Author Affiliation(s): Robert Huizinga, RN, CNeph(C), is Director of Clinical Research, Isotechnika Inc., Edmonton, Alberta. Therese Voyer, RN, BScN, CNeph(C), is Nephrology Nurse Clinician (Renal Transplant), University of Alberta Hospital, Edmonton, Alberta